e-Drug3D

1535

M FIDAXOMICIN

INN
FIDAXOMICIN

cas 1030825-28-5

CLASS

ANTIINFECTIVES
MACROLIDE
TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED DIARRHEA
INHIBITOR RNA SYNTHESIS BY RNA POLYMERASES

ROUTE (list)

ATC code

A07AA12

PK parameters

Tmax 1.02 HOUR
t1/2 11.2 HOUR

Target

TARGET BETA SUBUNIT OF RNA POLYMERASE

DrugCentral

DNA-directed RNA polymerase UNIPROT Q182S6 rpoZ

Download SDF file

Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-L-mannopyranosyl]oxy]methyl]-12-[(6-deoxy-5-C-methyl-β-D-lyxo-hexopyranosyl)oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S,9E,11S,12R,13E,15E,18S)-

Formula:
C48H68Cl2O17

Calculated chemical properties:

MW 987.92
NB_atoms 67
XLogP 5.03
PSA 247.113
NB_HD 8
NB_HA 17
fsp3 0.62
Lipinski(0=no;1=yes) 0

FDA
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