e-Drug3D

1534

M TAFLUPROST

INN
TAFLUPROST

cas 209860-88-8

CLASS

OPEN-ANGLE GLAUCOMA
OCULAR HYPERTENSION
PROSTAGLANDIN ANALOG
FP PROSTANOID RECEPTOR AGONIST

ROUTE (list)

ATC code

S01EE05

PK parameters

Tmax 0.16 HOUR
PPB 99 PERCENT

Target

TARGET FP PROSTANOID RECEPTOR

PDB
8IUM (CRYO-EM STRUCTURE OF THE TAFLUPROST ACID-BOUND HUMAN PTGFR-GQ COMPLEX)

Download experimental 3D coordinates of S2F with added hydrogens

Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR

Download SDF file

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5Z)-

Formula:
C22H28F2O5

Calculated chemical properties:

MW 409.44
NB_atoms 29
XLogP 2.48
PSA 86.717
NB_HD 2
NB_HA 5
fsp3 0.50
Lipinski(0=no;1=yes) 1

FDA
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