e-Drug3D

1521

cas 130308-48-4

CLASS

BLOOD
PEPTIDE
INFLAMMATION
PAIN
HEREDITARY ANGIOEDEMA
BRADYKININ B2 RECEPTOR ANTAGONIST

ROUTE (list)

SUBCUTANEOUS

PK parameters

F 97 PERCENT (30 MILLIGRAM)
VD 29 LITER
Cl 14.7 LITER / HOUR
t1/2 1.4 HOUR

MW 1306.58
NB_atoms 92
XLogP -11.19
PSA 474.544
NB_HD 24
NB_HA 29
fsp3 0.61
Lipinski(0=no;1=yes) 0

FDA
NDA 022150 (pdf not found) INN (ICATIBANT ACETATE) FIRAZYR (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2011 NEWMOLECULARENTITY
NDA 210118 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2019
NDA 208317 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2020
NDA 211021 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2020
NDA 212446 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (CIPLA) APPROVAL= AP YEAR= 2020
NDA 211501 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (WILSHIRE PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212081 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (NANG KUANG PHARM CO) APPROVAL= AP YEAR= 2020
NDA 213054 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (CAPLIN) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213222 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213521 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2023
NDA 213773 (pdf not found) INN (ICATIBANT ACETATE) ICATIBANT ACETATE (ALEMBIC) APPROVAL= AP YEAR= 2024