e-Drug3D
1520
DEFERIPRONE
INN
DEFERIPRONE
cas 30652-11-0
CLASS
VARIOUS
IRON CHELATOR
CHELATING AGENT
THALASSEMIA
ROUTE (list)
ORAL
ATC code
V03AC02
PK parameters
VD 104 LITER (65 KILOGRAM)
Cl 37.9 LITER / HOUR (EQN)
PPB 10 PERCENT
t1/2 1.9 HOUR
Solubility
SPARINGLY SOLUBLE IN DEIONIZED WATER
TARGET FERRIC ION (IRON III)
Unknown
Formula:
C7H9NO2
Calculated chemical properties:
MW 139.15
NB_atoms 10
XLogP 0.40
PSA 39.937
NB_HD 1
NB_HA 3
fsp3 0.29
Lipinski(0=no;1=yes) 1
NB_atoms 10
XLogP 0.40
PSA 39.937
NB_HD 1
NB_HA 3
fsp3 0.29
Lipinski(0=no;1=yes) 1
FDA
NDA 021825 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2011 NEWMOLECULARENTITY
NDA 208030 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2015
NDA 208800 (pdf not found) INN (DEFERIPRONE) DEFERIPRONE (TARO) APPROVAL= AP YEAR= 2019
NDA 212269 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2020
NDA 213239 (pdf not found) INN (DEFERIPRONE) DEFERIPRONE (HIKMA) APPROVAL= AP YEAR= 2021
NDA 021825 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2011 NEWMOLECULARENTITY
NDA 208030 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2015
NDA 208800 (pdf not found) INN (DEFERIPRONE) DEFERIPRONE (TARO) APPROVAL= AP YEAR= 2019
NDA 212269 (label) INN (DEFERIPRONE) FERRIPROX (CHIESI) APPROVAL= AP YEAR= 2020
NDA 213239 (pdf not found) INN (DEFERIPRONE) DEFERIPRONE (HIKMA) APPROVAL= AP YEAR= 2021