e-Drug3D
1519
cas 154229-18-2
CLASS
ANTINEOPLASTIC
METASTATIC CASTRATION-RESISTANT PROSTATE CANCER
INHIBITOR OF CYP17
ROUTE (list)
ORAL
PK parameters
Solubility
PRACTICALLY INSOLUBLE IN WATER
TARGET 17 ALPHA-HYDROXYLASE/C17,20-LYASE (CYP17)
Steroid 17-alpha-hydroxylase,17,20 lyase UNIPROT P05093 CYP17A1
Formula:
C26H33NO2
Calculated chemical properties:
MW 391.53
NB_atoms 29
XLogP 5.97
PSA 36.007
NB_HD 0
NB_HA 3
fsp3 0.62
Lipinski(0=no;1=yes) 0
NB_atoms 29
XLogP 5.97
PSA 36.007
NB_HD 0
NB_HA 3
fsp3 0.62
Lipinski(0=no;1=yes) 0
FDA
NDA 202379 (label) INN (ABIRATERONE ACETATE) ZYTIGA (JANSSEN BIOTECH) APPROVAL= AP YEAR= 2011
NDA 210308 (label) INN (ABIRATERONE ACETATE) YONSA (SUN PHARM) APPROVAL= AP YEAR= 2018
NDA 208339 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (HIKMA) APPROVAL= AP YEAR= 2018
NDA 208432 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 208446 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (MYLAN) APPROVAL= AP YEAR= 2018
NDA 208453 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (APOTEX) APPROVAL= AP YEAR= 2018
NDA 208327 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2019
NDA 208371 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (RISING) APPROVAL= AP YEAR= 2019
NDA 208380 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2019
NDA 209227 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2019
NDA 210686 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (MSN) APPROVAL= AP YEAR= 2019
NDA 212462 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (QILU) APPROVAL= AP YEAR= 2019
NDA 208416 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212206 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215947 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (NOVUGEN) APPROVAL= AP YEAR= 2022
NDA 210726 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 215086 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (FLORIDA) APPROVAL= AP YEAR= 2023
NDA 216793 (label) INN (ABIRATERONE ACETATE ; NIRAPARIB TOSYLATE) AKEEGA (JANSSEN BIOTECH) APPROVAL= AP YEAR= 2023
NDA 202379 (label) INN (ABIRATERONE ACETATE) ZYTIGA (JANSSEN BIOTECH) APPROVAL= AP YEAR= 2011
NDA 210308 (label) INN (ABIRATERONE ACETATE) YONSA (SUN PHARM) APPROVAL= AP YEAR= 2018
NDA 208339 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (HIKMA) APPROVAL= AP YEAR= 2018
NDA 208432 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 208446 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (MYLAN) APPROVAL= AP YEAR= 2018
NDA 208453 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (APOTEX) APPROVAL= AP YEAR= 2018
NDA 208327 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2019
NDA 208371 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (RISING) APPROVAL= AP YEAR= 2019
NDA 208380 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2019
NDA 209227 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2019
NDA 210686 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (MSN) APPROVAL= AP YEAR= 2019
NDA 212462 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (QILU) APPROVAL= AP YEAR= 2019
NDA 208416 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212206 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215947 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (NOVUGEN) APPROVAL= AP YEAR= 2022
NDA 210726 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 215086 (pdf not found) INN (ABIRATERONE ACETATE) ABIRATERONE ACETATE (FLORIDA) APPROVAL= AP YEAR= 2023
NDA 216793 (label) INN (ABIRATERONE ACETATE ; NIRAPARIB TOSYLATE) AKEEGA (JANSSEN BIOTECH) APPROVAL= AP YEAR= 2023