e-Drug3D

1512

AZILSARTAN KAMEDOXOMIL

INN
AZILSARTAN KAMEDOXOMIL

cas 863031-21-4

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN II RECEPTOR BLOCKER
SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

ATC code

C09CA09
C09DA09

PK parameters

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET AT1 RECEPTOR

DrugCentral

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

Download SDF file

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

Formula:
C30H24N4O8

Calculated chemical properties:

MW 568.53
NB_atoms 42
XLogP 4.71
PSA 133.883
NB_HD 1
NB_HA 12
fsp3 0.17
Lipinski(0=no;1=yes) 0

FDA
NDA 200796 (pdf not found) INN (AZILSARTAN KAMEDOXOMIL) EDARBI (AZURITY) APPROVAL= AP YEAR= 2011 NEWMOLECULARENTITY
NDA 202331 (pdf not found) INN (AZILSARTAN KAMEDOXOMIL ; CHLORTHALIDONE) EDARBYCLOR (AZURITY) APPROVAL= AP YEAR= 2011
NDA 214489 (pdf not found) INN (AZILSARTAN KAMEDOXOMIL) AZILSARTAN MEDOXOMIL (LUPIN LTD) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 217490 (pdf not found) INN (AZILSARTAN KAMEDOXOMIL ; CHLORTHALIDONE) AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2025
NDA 219062 (pdf not found) INN (AZILSARTAN MEDOXOMIL) AZILSARTAN MEDOXOMIL (HETERO LABS LIMITED) APPROVAL= TA YEAR= 2025