e-Drug3D
1487
cas 199739-10-1
CLASS
NERVOUS SYSTEM
ANTIPSYCHOTIC
SCHIZOPHRENIA
BENZISOXAZOLE DERIVATIVES
DOPAMINE D2 RECEPTOR ANTAGONIST
SEROTONIN TYPE 2 (5HT2A) RECEPTOR ANTAGONIST
ROUTE (list)
INTRAMUSCULAR
ATC code
N05AX13
PK parameters
Solubility
VERY SLIGHTLY SOLUBLE IN ETHANOL
TARGET 5-HYDROXYTRYPTAMINE 2A RECEPTOR
D(2) DOPAMINE RECEPTOR
ALPHA1 ADRENERGIC RECEPTOR
ALPHA2 ADRENERGIC RECEPTOR
H1 HISTAMINERGIC RECEPTOR
D(2) dopamine receptor UNIPROT P14416 DRD2
5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A
Formula:
C39H57FN4O4
Calculated chemical properties:
MW 664.89
NB_atoms 48
XLogP 9.11
PSA 83.131
NB_HD 0
NB_HA 8
fsp3 0.69
Lipinski(0=no;1=yes) 0
NB_atoms 48
XLogP 9.11
PSA 83.131
NB_HD 0
NB_HA 8
fsp3 0.69
Lipinski(0=no;1=yes) 0
FDA
NDA 022264 (pdf not found) INN (PALIPERIDONE PALMITATE) INVEGA SUSTENNA (JANSSEN PHARMS) APPROVAL= AP YEAR= 2009
NDA 207946 (pdf not found) INN (PALIPERIDONE PALMITATE) INVEGA TRINZA (JANSSEN PHARMS) APPROVAL= AP YEAR= 2015
NDA 211149 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2021
NDA 211995 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (TOLMAR) APPROVAL= TA YEAR= 2023
NDA 210397 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (PHARMASCIENCE INC) APPROVAL= TA YEAR= 2024
NDA 216228 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (MYLAN PHARMS INC) APPROVAL= TA YEAR= 2024
NDA 215682 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (MYLAN PHARMACEUTICALS INC A VIATRIS CO) APPROVAL= TA YEAR= 2024
NDA 216352 (pdf not found) INN (PALIPERIDONE PALMITATE) ERZOFRI (LUYE INNOMIND PHARMA) APPROVAL= AP YEAR= 2024
NDA 216674 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (ACCORD HLTHCARE INC) APPROVAL= TA YEAR= 2025
NDA 022264 (pdf not found) INN (PALIPERIDONE PALMITATE) INVEGA SUSTENNA (JANSSEN PHARMS) APPROVAL= AP YEAR= 2009
NDA 207946 (pdf not found) INN (PALIPERIDONE PALMITATE) INVEGA TRINZA (JANSSEN PHARMS) APPROVAL= AP YEAR= 2015
NDA 211149 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2021
NDA 211995 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (TOLMAR) APPROVAL= TA YEAR= 2023
NDA 210397 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (PHARMASCIENCE INC) APPROVAL= TA YEAR= 2024
NDA 216228 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (MYLAN PHARMS INC) APPROVAL= TA YEAR= 2024
NDA 215682 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (MYLAN PHARMACEUTICALS INC A VIATRIS CO) APPROVAL= TA YEAR= 2024
NDA 216352 (pdf not found) INN (PALIPERIDONE PALMITATE) ERZOFRI (LUYE INNOMIND PHARMA) APPROVAL= AP YEAR= 2024
NDA 216674 (pdf not found) INN (PALIPERIDONE PALMITATE) PALIPERIDONE PALMITATE (ACCORD HLTHCARE INC) APPROVAL= TA YEAR= 2025