e-Drug3D
1479
BEPOTASTINE
INN
BEPOTASTINE
cas 125602-71-3
CLASS
ANTI-ALLERGIC
ANTIHISTAMINES
HISTAMINE H1 ANTAGONIST
CONJUNCTIVITIS
ITCHING
SENSORY
ROUTE (list)
OPHTHALMIC
ATC code
PK parameters
Tmax 1.5 HOUR
PPB 55 PERCENT
TARGET HISTAMINE H1 RECEPTOR
Histamine H1 receptor UNIPROT P35367 HRH1
Formula:
C21H25ClN2O3
Calculated chemical properties:
MW 387.87
NB_atoms 27
XLogP 2.84
PSA 59.304
NB_HD 0
NB_HA 5
fsp3 0.43
Lipinski(0=no;1=yes) 1
NB_atoms 27
XLogP 2.84
PSA 59.304
NB_HD 0
NB_HA 5
fsp3 0.43
Lipinski(0=no;1=yes) 1
FDA
NDA 022288 (label) INN (BEPOTASTINE BESILATE) BEPREVE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 2009 NEWMOLECULARENTITY
NDA 206080 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (SANDOZ INC) APPROVAL= TA YEAR= 2017
NDA 206066 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (APOTEX) APPROVAL= AP YEAR= 2019
NDA 206220 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (MYLAN) APPROVAL= AP YEAR= 2019
NDA 214588 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (ALEMBIC) APPROVAL= AP YEAR= 2023
NDA 217770 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 022288 (label) INN (BEPOTASTINE BESILATE) BEPREVE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 2009 NEWMOLECULARENTITY
NDA 206080 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (SANDOZ INC) APPROVAL= TA YEAR= 2017
NDA 206066 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (APOTEX) APPROVAL= AP YEAR= 2019
NDA 206220 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (MYLAN) APPROVAL= AP YEAR= 2019
NDA 214588 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (ALEMBIC) APPROVAL= AP YEAR= 2023
NDA 217770 (pdf not found) INN (BEPOTASTINE BESILATE) BEPOTASTINE BESILATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024