e-Drug3D
147
WARFARIN
INN
WARFARIN
cas 81-81-2
CLASS
BLOOD
ANTICOAGULANT
COUMARIN DERIVATIVES
ROUTE (list)
ORAL INJECTION
ATC code
B01AA03
PK parameters
VD 8.4 LITER (65 KILOGRAM)
Cl 0.21 LITER / HOUR (65 KILOGRAM)
PPB 98 PERCENT
t1/2 29 HOUR
Solubility
SOLUBLE IN WATER
TARGET VITAMIN K EPOXIDE REDUCTASE COMPLEX
Vitamin K epoxide reductase complex subunit 1 UNIPROT Q9BQB6 VKORC1
Formula:
C19H16O4
Calculated chemical properties:
MW 308.32
NB_atoms 23
XLogP 3.61
PSA 57.287
NB_HD 1
NB_HA 4
fsp3 0.16
Lipinski(0=no;1=yes) 1
NB_atoms 23
XLogP 3.61
PSA 57.287
NB_HD 1
NB_HA 4
fsp3 0.16
Lipinski(0=no;1=yes) 1
FDA
NDA 011771 (pdf not found) INN (WARFARIN POTASSIUM) ATHROMBIN-K (PHARM RES ASSOC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086118 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086119 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086120 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086122 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086123 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088719 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088720 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088721 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009218 (pdf not found) INN (WARFARIN SODIUM) COUMADIN (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1954 DISCONTINUED
NDA 017020 (pdf not found) INN (WARFARIN SODIUM) PANWARFIN (ABBOTT) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 040145 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (BARR) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040196 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040301 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (TARO) APPROVAL= AP YEAR= 1999
NDA 040416 (pdf not found) INN (WARFARIN SODIUM) JANTOVEN (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2003
NDA 040415 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 040616 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (PLIVA) APPROVAL= AP YEAR= 2006
NDA 040663 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (ZYDUS PHARMS USA) APPROVAL= AP YEAR= 2006
NDA 090935 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (INVAGEN PHARMS) APPROVAL= AP YEAR= 2011
NDA 200104 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AIPING PHARM INC) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202202 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2013
NDA 011771 (pdf not found) INN (WARFARIN POTASSIUM) ATHROMBIN-K (PHARM RES ASSOC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086118 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086119 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086120 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086122 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086123 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088719 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088720 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088721 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009218 (pdf not found) INN (WARFARIN SODIUM) COUMADIN (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1954 DISCONTINUED
NDA 017020 (pdf not found) INN (WARFARIN SODIUM) PANWARFIN (ABBOTT) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 040145 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (BARR) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040196 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040301 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (TARO) APPROVAL= AP YEAR= 1999
NDA 040416 (pdf not found) INN (WARFARIN SODIUM) JANTOVEN (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2003
NDA 040415 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 040616 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (PLIVA) APPROVAL= AP YEAR= 2006
NDA 040663 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (ZYDUS PHARMS USA) APPROVAL= AP YEAR= 2006
NDA 090935 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (INVAGEN PHARMS) APPROVAL= AP YEAR= 2011
NDA 200104 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AIPING PHARM INC) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202202 (pdf not found) INN (WARFARIN SODIUM) WARFARIN SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2013