e-Drug3D
1434
cas 172673-20-0
CLASS
METABOLISM
ANTIEMETIC
P/NEUROKININ-1 (NK1) RECEPTOR ANTAGONIST
ROUTE (list)
INTRAVENOUS
ATC code
A04AD12
PK parameters
Solubility
FREELY SOLUBLE IN WATER
TARGET P/NEUROKININ-1 (NK1) RECEPTOR
Substance-P receptor UNIPROT P25103 TACR1
Formula:
C23H22F7N4O6P
Calculated chemical properties:
MW 612.40
NB_atoms 41
XLogP 3.10
PSA 122.026
NB_HD 1
NB_HA 10
fsp3 0.39
Lipinski(0=no;1=yes) 0
NB_atoms 41
XLogP 3.10
PSA 122.026
NB_HD 1
NB_HA 10
fsp3 0.39
Lipinski(0=no;1=yes) 0
FDA
NDA 022023 (label) INN (FOSAPREPITANT DIMEGLUMINE) EMEND (MERCK AND CO INC) APPROVAL= AP YEAR= 2008 NEWMOLECULARENTITY
NDA 206197 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2016
NDA 204845 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (SAGENT PHARMS) APPROVAL= TA YEAR= 2017
NDA 210064 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2019
NDA 209965 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (MSN) APPROVAL= AP YEAR= 2019
NDA 204015 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2019
NDA 205020 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (APOTEX) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210689 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (LUPIN LTD) APPROVAL= AP YEAR= 2019
NDA 211624 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (GENEYORK PHARMS) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211860 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2019
NDA 212309 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (BE PHARMS) APPROVAL= AP YEAR= 2019
NDA 203939 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (SANDOZ) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 204025 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 211160 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212957 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (NAVINTA LLC) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213106 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2020
NDA 210625 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (EUGIA PHARMA) APPROVAL= AP YEAR= 2021
NDA 212143 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (CHIA TAI TIANQING) APPROVAL= AP YEAR= 2021
NDA 213199 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (PRAXGEN) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214616 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (ASPIRO) APPROVAL= AP YEAR= 2021
NDA 214683 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (PIRAMAL CRITICAL) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 216686 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOCINVEZ (STERISCIENCE) APPROVAL= AP YEAR= 2023
NDA 022023 (label) INN (FOSAPREPITANT DIMEGLUMINE) EMEND (MERCK AND CO INC) APPROVAL= AP YEAR= 2008 NEWMOLECULARENTITY
NDA 206197 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2016
NDA 204845 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (SAGENT PHARMS) APPROVAL= TA YEAR= 2017
NDA 210064 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2019
NDA 209965 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (MSN) APPROVAL= AP YEAR= 2019
NDA 204015 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2019
NDA 205020 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (APOTEX) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210689 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (LUPIN LTD) APPROVAL= AP YEAR= 2019
NDA 211624 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (GENEYORK PHARMS) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211860 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2019
NDA 212309 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (BE PHARMS) APPROVAL= AP YEAR= 2019
NDA 203939 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (SANDOZ) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 204025 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 211160 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212957 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (NAVINTA LLC) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213106 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2020
NDA 210625 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (EUGIA PHARMA) APPROVAL= AP YEAR= 2021
NDA 212143 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (CHIA TAI TIANQING) APPROVAL= AP YEAR= 2021
NDA 213199 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (PRAXGEN) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214616 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (ASPIRO) APPROVAL= AP YEAR= 2021
NDA 214683 (pdf not found) INN (FOSAPREPITANT DIMEGLUMINE) FOSAPREPITANT DIMEGLUMINE (PIRAMAL CRITICAL) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 216686 (label) INN (FOSAPREPITANT DIMEGLUMINE) FOCINVEZ (STERISCIENCE) APPROVAL= AP YEAR= 2023