e-Drug3D

1425

CEFDITOREN PIVOXIL

DISCONTINUED

INN
CEFDITOREN PIVOXIL

(has an active metabolite)

cas 117467-28-4

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS
INHIBITOR

ROUTE (list)

ORAL

ATC code

J01DD16

PK parameters

F 14 PERCENT

Solubility

< 0.1 MILLIGRAM / MILLILITER IN WATER

Target

TARGET PENICILLIN-BINDING PROTEIN

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-

Formula:
C25H28N6O7S3

Calculated chemical properties:

MW 620.74
NB_atoms 41
XLogP 2.30
PSA 161.1
NB_HD 3
NB_HA 13
fsp3 0.40
Lipinski(0=no;1=yes) 0

FDA
NDA 021222 (label) INN (CEFDITOREN PIVOXIL) SPECTRACEF (VANSEN PHARMA) APPROVAL= AP YEAR= 2001 NEWMOLECULARENTITY DISCONTINUED