e-Drug3D

1421

PIPERONYL BUTOXIDE

DISCONTINUED

INN
PIPERONYL BUTOXIDE

cas 51-03-6

CLASS

ANTIPARASITIC
HEAD LICE
INHIBIT MONO-OXYGENASES AND NONSPECIFIC ESTERASES (PMID17192611)
PIPERONYL BUTOXIDE ITSELF HAS LIMITED INSECTICIDAL ACTIVITY. ITS SYNERGISTIC INTERACTION WITH PYRETHROIDS TAKES PLACES AT THE MICROSOMAL LEVEL. THE DETAILED MECHANISM HAS NOT BEEN FULLY CLARIFIED.

ROUTE (list)

TOPICAL

ATC code

PK parameters

Target

TARGET MONO-OXYGENASE
ESTERASE

DrugCentral

Cytochrome P450 UNIPROT E0V9R7

Download SDF file

1,3-Benzodioxole, 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-

Formula:
C19H30O5

Calculated chemical properties:

MW 338.43
NB_atoms 24
XLogP 3.72
PSA 53.014
NB_HD 0
NB_HA 5
fsp3 0.68
Lipinski(0=no;1=yes) 1

FDA
NDA 021043 (pdf not found) INN (PIPERONYL BUTOXIDE ; PYRETHRINS) RID MOUSSE (BAYER HEALTHCARE LLC) APPROVAL= AP YEAR= 2000 DISCONTINUED