e-Drug3D

1407

cas 56211-40-6

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE AGENTS
DIURETICS
ANTIINFLAMMATORY
INHIBITOR OF THE NA+/K+/2CL- CARRIER SYSTEM IN NEPHRON
TREATMENT OF EDEMA ASSOCIATED WITH CONGESTIVE HEART FAILURE, RENAL DISEASE, OR HEPATIC DISEASE

ROUTE (list)

ORAL INTRAVENOUS

PK parameters

F 80 PERCENT
VD 13.5 LITER
Cl 2.6 LITER / HOUR (EQN)
PPB 99 PERCENT
t1/2 3.5 HOUR

MW 348.43
NB_atoms 24
XLogP 2.53
PSA 94.047
NB_HD 3
NB_HA 7
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
NDA 020136 (label) INN (TORSEMIDE) DEMADEX (PHARMOBEDIENT) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 020137 (pdf not found) INN (TORSEMIDE) DEMADEX (ROCHE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 076110 (pdf not found) INN (TORSEMIDE) TORSEMIDE (TEVA) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076226 (pdf not found) INN (TORSEMIDE) TORSEMIDE (STRIDES PHARMA) APPROVAL= AP YEAR= 2003
NDA 076346 (pdf not found) INN (TORSEMIDE) TORSEMIDE (PLIVA PHARM IND) APPROVAL= AP YEAR= 2003
NDA 076894 (pdf not found) INN (TORSEMIDE) TORSEMIDE (COREPHARMA) APPROVAL= AP YEAR= 2005
NDA 076943 (pdf not found) INN (TORSEMIDE) TORSEMIDE (HIKMA) APPROVAL= AP YEAR= 2005
NDA 078249 (pdf not found) INN (TORSEMIDE) TORSEMIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 078007 (pdf not found) INN (TORSEMIDE) TORSEMIDE (HIKMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078478 (pdf not found) INN (TORSEMIDE) TORSEMIDE (SUN PHARM INDS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 079234 (pdf not found) INN (TORSEMIDE) TORSEMIDE (HETERO LABS LTD III) APPROVAL= AP YEAR= 2009
NDA 090656 (pdf not found) INN (TORSEMIDE) TORSEMIDE (AM REGENT) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090613 (pdf not found) INN (TORSEMIDE) TORSEMIDE (STRIDES PHARMA) APPROVAL= AP YEAR= 2011
NDA 213218 (label) INN (TORSEMIDE) SOAANZ (SARFE PHARMS) APPROVAL= AP YEAR= 2021