e-Drug3D

1404

COLFOSCERIL PALMITATE

DISCONTINUED

INN
COLFOSCERIL PALMITATE

cas 63-89-8

CLASS

RESPIRATORY
LUNG SURFACTANTS

ROUTE (list)

INTRATRACHEAL

ATC code

R07AA01

PK parameters

Target

PDB
2YGO (WIF DOMAIN-EGF-LIKE DOMAIN 1 OF HUMAN WNT INHIBITORY FACTOR 1 IN COMPLEX WITH 1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE)

Ligand code = PCF (link to the list of PDB complexes)

Download experimental 3D coordinates of PCF with added hydrogens

DrugCentral

Unknown

Download SDF file

3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-

Formula:
C40H80NO8P

Calculated chemical properties:

MW 734.02
NB_atoms 50
XLogP 10.61
PSA 100.572
NB_HD 0
NB_HA 8
fsp3 0.95
Lipinski(0=no;1=yes) 0

FDA
NDA 020044 (pdf not found) INN (CETYL ALCOHOL ; COLFOSCERIL PALMITATE ; TYLOXAPOL) EXOSURF NEONATAL (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1990 DISCONTINUED