e-Drug3D

1397

cas 1953-02-2

CLASS

RESPIRATORY
MUCOLYTIC
EXPECTORANT
USED TO CONTROL THE RATE OF CYSTINE PRECIPITATION AND EXCRETION IN THE DISEASE CYSTINURIA

ROUTE (list)

ORAL

PK parameters

Tmax 3 HOUR

MW 162.19
NB_atoms 10
XLogP -1.83
PSA 63.691
NB_HD 1
NB_HA 4
fsp3 0.60
Lipinski(0=no;1=yes) 1

FDA
NDA 019569 (pdf not found) INN (TIOPRONIN) THIOLA (MISSION PHARMA) APPROVAL= AP YEAR= 1988 NEWMOLECULARENTITY
NDA 211843 (pdf not found) INN (TIOPRONIN) THIOLA EC (MISSION PHARMACAL) APPROVAL= AP YEAR= 2019
NDA 214326 (pdf not found) INN (TIOPRONIN) TIOPRONIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021
NDA 216198 (pdf not found) INN (TIOPRONIN) TIOPRONIN (PH HEALTH) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 217219 (pdf not found) INN (TIOPRONIN) TIOPRONIN (PH HEALTH) APPROVAL= AP YEAR= 2023
NDA 216278 (pdf not found) INN (TIOPRONIN) TIOPRONIN (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 216990 (pdf not found) INN (TIOPRONIN) TIOPRONIN (TORRENT) APPROVAL= AP YEAR= 2024
NDA 216456 (pdf not found) INN (TIOPRONIN) TIOPRONIN (TEVA PHARMS INC) APPROVAL= AP YEAR= 2024