e-Drug3D
1393
INAMRINONE
INN
INAMRINONE
cas 60719-84-8
CLASS
CARDIOVASCULAR
PHOSPHODIESTERASE INHIBITORS
VASODILATOR AGENTS
CARDIOTONIC
ROUTE (list)
INJECTION
ATC code
C01CE01
PK parameters
VD 84.5 LITER (65 KILOGRAM)
Cl 34.7 LITER / HOUR (65 KILOGRAM)
PPB 11 PERCENT
t1/2 2 HOUR
TARGET PHOSPHODIESTERASE 3
cGMP-inhibited 3,5-cyclic phosphodiesterase A UNIPROT Q14432 PDE3A
Formula:
C10H9N3O
Calculated chemical properties:
MW 187.20
NB_atoms 14
XLogP 1.02
PSA 64.663
NB_HD 3
NB_HA 4
fsp3 0.00
Lipinski(0=no;1=yes) 1
NB_atoms 14
XLogP 1.02
PSA 64.663
NB_HD 3
NB_HA 4
fsp3 0.00
Lipinski(0=no;1=yes) 1
FDA
NDA 018700 (pdf not found) INN (INAMRINONE LACTATE) INOCOR (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 074616 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (HOSPIRA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075513 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (HIKMA) APPROVAL= AP YEAR= 2000
NDA 075542 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 018700 (pdf not found) INN (INAMRINONE LACTATE) INOCOR (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 074616 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (HOSPIRA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075513 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (HIKMA) APPROVAL= AP YEAR= 2000
NDA 075542 (pdf not found) INN (INAMRINONE LACTATE) AMRINONE LACTATE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2000 DISCONTINUED