e-Drug3D

1386

CLOCORTOLONE PIVALATE

INN
CLOCORTOLONE PIVALATE

cas 34097-16-0

CLASS

DERMATOLOGICALS
CORTICOSTEROID
ANTIINFLAMMATORY
ANTI-PRURITIC
VASOCONTRICTIVE
GLUCOCORTICOID

ROUTE (list)

TOPICAL

ATC code

D07AB21

PK parameters

Target

TARGET GLUCOCORTICOID RECEPTOR

DrugCentral

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

Pregna-1,4-diene-3,20-dione, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-

Formula:
C27H36ClFO5

Calculated chemical properties:

MW 495.01
NB_atoms 34
XLogP 4.60
PSA 69.997
NB_HD 1
NB_HA 5
fsp3 0.74
Lipinski(0=no;1=yes) 1

FDA
NDA 017765 (label) INN (CLOCORTOLONE PIVALATE) CLODERM (LEGACY PHARMA) APPROVAL= AP YEAR= 1977
NDA 206370 (pdf not found) INN (CLOCORTOLONE PIVALATE) CLOCORTOLONE PIVALATE (TARO) APPROVAL= AP YEAR= 2020