e-Drug3D

1371

cas 50370-12-2

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

ORAL

PK parameters

VD 14.9 LITER (65 KILOGRAM)
Cl 9.7 LITER / HOUR (65 KILOGRAM)
PPB 61 PERCENT
t1/2 1.1 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B
OLIGOPEPTIDE TRANSPORTER, SMALL INTESTINE ISOFORM
OLIGOPEPTIDE TRANSPORTER, KIDNEY ISOFORM

PDB
9BIR (CRYO-EM STRUCTURE OF THE MAMMALIAN PEPTIDE TRANSPORTER PEPT2 BOUND TO CEFADROXIL)

Ligand code = A1APP (link to the list of PDB complexes)

Download experimental 3D coordinates of A1APP with added hydrogens

MW 362.39
NB_atoms 25
XLogP -1.18
PSA 123.278
NB_HD 4
NB_HA 8
fsp3 0.31
Lipinski(0=no;1=yes) 1

FDA
NDA 062334 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062376 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) ULTRACEF (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062378 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) ULTRACEF (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062390 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) ULTRACEF (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062408 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) ULTRACEF (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050512 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) DURICEF (WARNER CHILCOTT) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 050527 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) DURICEF (WARNER CHILCOTT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 050528 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) DURICEF (WARNER CHILCOTT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062291 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (SANDOZ) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062766 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062774 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (TEVA PHARMS) APPROVAL= AP YEAR= 1987
NDA 062695 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (TEVA) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 062698 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (ANI PHARMS) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063017 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (PUREPAC PHARM) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 065015 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (RANBAXY LABS LTD) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 065018 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (RANBAXY) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 065115 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 065260 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (HIKMA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065278 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (ANI PHARMS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065282 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (TEVA PHARMS) APPROVAL= AP YEAR= 2006
NDA 065301 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (CHARTWELL RX) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065307 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (CHARTWELL RX) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065309 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (CHARTWELL RX) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065311 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (HIKMA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065352 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 065392 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (LUPIN) APPROVAL= AP YEAR= 2007
NDA 065396 (label) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (LUPIN) APPROVAL= AP YEAR= 2008
NDA 091036 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (HIKMA PHARMS) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 065349 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (AUROBINDO) APPROVAL= AP YEAR= 2013
NDA 205072 (pdf not found) INN (CEFADROXIL/CEFADROXIL HEMIHYDRATE) CEFADROXIL (CSPC OUYI) APPROVAL= AP YEAR= 2017 DISCONTINUED