e-Drug3D

1365

cas 100-97-0

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
METHENAMINE COMPONENT IS HYDROLYZED TO FORMALDEHYDE IN ACID URINE
MICROORGANISMS DO NOT DEVELOP RESISTANCE TO FORMALDEHYDE

ROUTE (list)

ORAL

PK parameters

MW 140.20
NB_atoms 10
XLogP -1.02
PSA 23.602
NB_HD 0
NB_HA 4
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 016151 (label) INN (METHENAMINE HIPPURATE) UREX (QUAGEN) APPROVAL= AP YEAR= 1967
NDA 017681 (label) INN (METHENAMINE HIPPURATE) HIPREX (ESJAY PHARMA) APPROVAL= AP YEAR= 1976
NDA 076411 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (IMPAX LABS INC) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 205661 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2016
NDA 212172 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (MICRO LABS) APPROVAL= AP YEAR= 2019
NDA 210068 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (NOVAST LABS) APPROVAL= AP YEAR= 2020
NDA 217675 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (JUBILANT CADISTA) APPROVAL= AP YEAR= 2023
NDA 219661 (pdf not found) INN (METHENAMINE HIPPURATE) METHENAMINE HIPPURATE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2025