e-Drug3D
1362
cas 74050-97-8
CLASS
NERVOUS SYSTEM
ANTIPSYCHOTIC
DOPAMINE ANTAGONIST
DECANOATE ESTER OF THE BUTYROPHENONE
BLOCKS THE EFFECTS OF DOPAMINE
THE TREATMENT OF SCHIZOPHRENIC PATIENTS
BUTYROPHENONE DERIVATIVES
ROUTE (list)
INJECTION
ATC code
N05AD01
PK parameters
Solubility
ALMOST INSOLUBLE IN WATER 0.01 MILLIGRAM / MILLILITER
TARGET DOPAMINE D2 RECEPTOR
D(2) dopamine receptor UNIPROT P14416 DRD2
D(2) dopamine receptor UNIPROT P14416 DRD2
Formula:
C31H41ClFNO3
Calculated chemical properties:
MW 530.10
NB_atoms 37
XLogP 8.12
PSA 41.513
NB_HD 0
NB_HA 4
fsp3 0.55
Lipinski(0=no;1=yes) 0
NB_atoms 37
XLogP 8.12
PSA 41.513
NB_HD 0
NB_HA 4
fsp3 0.55
Lipinski(0=no;1=yes) 0
FDA
NDA 018701 (label) INN (HALOPERIDOL DECANOATE) HALDOL (JANSSEN PHARMS) APPROVAL= AP YEAR= 1986
NDA 074893 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1997
NDA 074811 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075305 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HIKMA) APPROVAL= AP YEAR= 1998
NDA 075393 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075176 (label) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HOSPIRA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075440 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2000
NDA 076463 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (SANDOZ) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 205241 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (GLAND) APPROVAL= AP YEAR= 2017
NDA 209101 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2018
NDA 211180 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2019
NDA 214507 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MEITHEAL) APPROVAL= AP YEAR= 2021
NDA 216730 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MANKIND PHARMA) APPROVAL= AP YEAR= 2023
NDA 219168 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (CAPLIN) APPROVAL= AP YEAR= 2025
NDA 018701 (label) INN (HALOPERIDOL DECANOATE) HALDOL (JANSSEN PHARMS) APPROVAL= AP YEAR= 1986
NDA 074893 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1997
NDA 074811 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075305 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HIKMA) APPROVAL= AP YEAR= 1998
NDA 075393 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075176 (label) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (HOSPIRA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075440 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2000
NDA 076463 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (SANDOZ) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 205241 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (GLAND) APPROVAL= AP YEAR= 2017
NDA 209101 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2018
NDA 211180 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2019
NDA 214507 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MEITHEAL) APPROVAL= AP YEAR= 2021
NDA 216730 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (MANKIND PHARMA) APPROVAL= AP YEAR= 2023
NDA 219168 (pdf not found) INN (HALOPERIDOL DECANOATE) HALOPERIDOL DECANOATE (CAPLIN) APPROVAL= AP YEAR= 2025