e-Drug3D

134

cas 499-67-2

CLASS

SENSORY
LOCAL ANESTHETIC

ROUTE (list)

OPHTHALMIC

PK parameters

MW 294.39
NB_atoms 21
XLogP 2.56
PSA 62.694
NB_HD 2
NB_HA 5
fsp3 0.56
Lipinski(0=no;1=yes) 1

FDA
NDA 008883 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) OPHTHAINE (APOTHECON) APPROVAL= AP YEAR= 1953 NEWMOLECULARENTITY DISCONTINUED
NDA 012583 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) OPHTHETIC (ALLERGAN) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 080027 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) ALCAINE (ALCON LABS INC) APPROVAL= AP YEAR= 1971
NDA 084144 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (SOLA BARNES HIND) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 084151 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (SOLA BARNES HIND) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 087681 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PARACAINE (OPTOPICS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088087 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) KAINAIR (PHARMAFAIR) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 040074 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1995
NDA 040277 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2000
NDA 215816 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 219136 (pdf not found) INN (PROPARACAINE HYDROCHLORIDE) PROPARACAINE HYDROCHLORIDE (MANKIND PHARMA) APPROVAL= AP YEAR= 2025