e-Drug3D
1326
ABAMETAPIR
DISCONTINUED
INN
ABAMETAPIR
cas 1762-34-1
CLASS
ANTIPARASITIC
PEDICULICIDE
TREATMENT OF HEAD LICE
METALLOPROTEINASE INHIBITOR
ROUTE (list)
TOPICAL
ATC code
P03AX07
PK parameters
Tmax 1.05 HOUR
PPB 91.8 PERCENT
t1/2 21 HOUR
TARGET METALLOPROTEINASE
PDB
5ARC (COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE)
Ligand code = EL3 (link to the list of PDB complexes)
Download experimental 3D coordinates of EL3 with added hydrogens
Unknown
Formula:
C12H12N2
Calculated chemical properties:
MW 184.24
NB_atoms 14
XLogP 2.76
PSA 19.182
NB_HD 0
NB_HA 2
fsp3 0.17
Lipinski(0=no;1=yes) 1
NB_atoms 14
XLogP 2.76
PSA 19.182
NB_HD 0
NB_HA 2
fsp3 0.17
Lipinski(0=no;1=yes) 1
FDA
NDA 206966 (pdf not found) INN (ABAMETAPIR) XEGLYZE (HATCHTECH) APPROVAL= AP YEAR= 2020 NEWMOLECULARENTITY DISCONTINUED
NDA 206966 (pdf not found) INN (ABAMETAPIR) XEGLYZE (HATCHTECH) APPROVAL= AP YEAR= 2020 NEWMOLECULARENTITY DISCONTINUED