e-Drug3D

1324

cas 146-17-8

CLASS

VITAMIN B2
SUPPLEMENT
METABOLISM
PARENTERAL NUTRITION

ROUTE (list)

INJECTION INTRAVENOUS OPHTHALMIC

PK parameters

TARGET CYTOCHROME B2 MITOCHONDRIAL

PDB
6CNY (2.3 ANGSTROM STRUCTURE OF PHOSPHODIESTERASE TREATED VIVID (COMPLEX WITH FMN))

Ligand code = FMN (link to the list of PDB complexes)

Download experimental 3D coordinates of FMN with added hydrogens

MW 454.33
NB_atoms 31
XLogP -2.87
PSA 193.6
NB_HD 4
NB_HA 13
fsp3 0.41
Lipinski(0=no;1=yes) 0

FDA
NDA 018933 (pdf not found) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) M.V.I.-12 LYOPHILIZED (TELIGENT PHARMA INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006071 (pdf not found) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) BEROCCA PN (ROCHE) APPROVAL= AP YEAR= 1947 DISCONTINUED
NDA 008809 (label) INN (RIBOFLAVIN) M.V.I.-12 ADULT (HOSPIRA) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 018440 (pdf not found) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) M.V.C. 9+3 (ABRAXIS PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018439 (pdf not found) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) MVC PLUS (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018920 (label) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) M.V.I. PEDIATRIC (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 021163 (label) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) INFUVITE ADULT (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2000
NDA 021559 (label) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) INFUVITE ADULT (SANDOZ INC) APPROVAL= AP YEAR= 2003 OBSOLETE
NDA 021625 (label) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) M.V.I. ADULT (HOSPIRA) APPROVAL= AP YEAR= 2004
NDA 021643 (label) INN (RIBOFLAVIN 5'-PHOSPHATE SODIUM) M.V.I. ADULT PHARMACY BULK PACKAGE (HOSPIRA) APPROVAL= AP YEAR= 2004 NEWAPPLICATION
NDA 203324 (label) INN (RIBOFLAVIN 5'-PHOSPHATE) PHOTREXA (GLAUKOS) APPROVAL= AP YEAR= 2016