e-Drug3D

1315

MEZLOCILLIN

DISCONTINUED

INN
MEZLOCILLIN

cas 51481-65-3

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
PENICILLINS

ROUTE (list)

INJECTION

ATC code

J01CA10

PK parameters

VD 5.8 LITER (65 KILOGRAM)
Cl 8.1 LITER / HOUR (65 KILOGRAM)
PPB 30 PERCENT
t1/2 1.2 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Formula:
C21H25N5O8S2

Calculated chemical properties:

MW 538.59
NB_atoms 36
XLogP -1.57
PSA 165.753
NB_HD 2
NB_HA 13
fsp3 0.48
Lipinski(0=no;1=yes) 0

FDA
NDA 062333 (pdf not found) INN (MEZLOCILLIN SODIUM MONOHYDRATE) MEZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062372 (pdf not found) INN (MEZLOCILLIN SODIUM MONOHYDRATE) MEZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062697 (pdf not found) INN (MEZLOCILLIN SODIUM MONOHYDRATE) MEZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050549 (pdf not found) INN (MEZLOCILLIN SODIUM MONOHYDRATE) MEZLIN (BAYER PHARMS) APPROVAL= AP YEAR= 1981 NEWMOLECULARENTITY DISCONTINUED