e-Drug3D

1306

cas 608137-32-2

CLASS

NERVOUS SYSTEM
L-LYSINE-D-AMPHETAMINE
PSYCHOSTIMULANT
CENTRAL NERVOUS SYSTEM STIMULANT INDICATED FOR THE TREATMENT OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)
A PRODRUG OF DEXTROAMPHETAMINE
BLOCK THE REUPTAKE OF NOREPINEPHRINE AND DOPAMINE INTO THE PRESYNAPTIC NEURON AND INCREASE THE RELEASE OF THESE MONOAMINES INTO THE EXTRANEURONAL SPACE

ROUTE (list)

ORAL

PK parameters

MW 263.38
NB_atoms 19
XLogP 1.19
PSA 77.459
NB_HD 5
NB_HA 4
fsp3 0.53
Lipinski(0=no;1=yes) 1

FDA
NDA 021977 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) VYVANSE (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2007
NDA 208510 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) VYVANSE (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2017
NDA 202827 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (HIKMA) APPROVAL= AP YEAR= 2023
NDA 202830 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 202835 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (MYLAN) APPROVAL= AP YEAR= 2023
NDA 202802 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2023
NDA 214547 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (NORWICH) APPROVAL= AP YEAR= 2023
NDA 215415 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (TEVA PHARMS) APPROVAL= AP YEAR= 2023
NDA 216944 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (APOTEX) APPROVAL= AP YEAR= 2023
NDA 211840 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (SPECGX LLC) APPROVAL= AP YEAR= 2023
NDA 214134 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2023
NDA 214484 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2023
NDA 215330 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (RHODES PHARMS) APPROVAL= AP YEAR= 2023
NDA 215802 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (LANNETT CO INC) APPROVAL= AP YEAR= 2023
NDA 216266 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (PRINSTON INC) APPROVAL= AP YEAR= 2023
NDA 217068 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 217194 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2023
NDA 217442 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 202836 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (SANDOZ) APPROVAL= AP YEAR= 2024
NDA 218306 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (MSN) APPROVAL= AP YEAR= 2024
NDA 218604 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (ELITE LABS INC) APPROVAL= AP YEAR= 2024
NDA 218850 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (SPECGX LLC) APPROVAL= AP YEAR= 2024
NDA 219258 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (GRANULES) APPROVAL= AP YEAR= 2024
NDA 218987 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) LISDEXAMFETAMINE DIMESYLATE (GRANULES) APPROVAL= AP YEAR= 2025
NDA 219847 (pdf not found) INN (LISDEXAMFETAMINE DIMESYLATE) ARYNTA (AZURITY) APPROVAL= AP YEAR= 2025