e-Drug3D
1275
EPROSARTAN
DISCONTINUED
INN
EPROSARTAN
cas 133040-01-4
CLASS
CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN II RECEPTOR ANTAGONIST
ROUTE (list)
ORAL
PK parameters
F 13 PERCENT
VD 308 LITER
Cl 48.5 LITER / HOUR
PPB 98 PERCENT
t1/2 20 HOUR
Solubility
INSOLUBLE IN WATER
TARGET TYPE-1 ANGIOTENSIN II RECEPTOR (AT1)
Type-1 angiotensin II receptor UNIPROT P30556 AGTR1
Formula:
C23H24N2O4S
Calculated chemical properties:
MW 422.50
NB_atoms 30
XLogP 2.07
PSA 83.615
NB_HD 0
NB_HA 6
fsp3 0.26
Lipinski(0=no;1=yes) 1
NB_atoms 30
XLogP 2.07
PSA 83.615
NB_HD 0
NB_HA 6
fsp3 0.26
Lipinski(0=no;1=yes) 1
FDA
NDA 020738 (label) INN (EPROSARTAN MESYLATE) TEVETEN (ABBVIE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 021268 (label) INN (EPROSARTAN MESYLATE ; HYDROCHLOROTHIAZIDE) TEVETEN HCT (ABBVIE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 202012 (pdf not found) INN (EPROSARTAN MESYLATE) EPROSARTAN MESYLATE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 020738 (label) INN (EPROSARTAN MESYLATE) TEVETEN (ABBVIE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 021268 (label) INN (EPROSARTAN MESYLATE ; HYDROCHLOROTHIAZIDE) TEVETEN HCT (ABBVIE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 202012 (pdf not found) INN (EPROSARTAN MESYLATE) EPROSARTAN MESYLATE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2011 DISCONTINUED