e-Drug3D

1267

DOLASETRON

DISCONTINUED

INN
DOLASETRON

(has an active metabolite)

cas 115956-12-2

CLASS

METABOLISM
SEROTONIN 5HT3 ANTAGONIST
ANTIEMETIC

ROUTE (list)

ORAL INJECTION

ATC code

A04AA04

PK parameters

Solubility

SLIGHTLY SOLUBLE IN NORMAL SALINE

Target

TARGET 5-HYDROXYTRYPTAMINE 3 RECEPTOR

DrugCentral

5-hydroxytryptamine receptor 3A UNIPROT P46098 HTR3A

Download SDF file

1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester

Formula:
C19H20N2O3

Calculated chemical properties:

MW 324.37
NB_atoms 24
XLogP 2.52
PSA 56.288
NB_HD 1
NB_HA 5
fsp3 0.47
Lipinski(0=no;1=yes) 1

FDA
NDA 020623 (pdf not found) INN (DOLASETRON MESYLATE) ANZEMET (VALIDUS PHARMS) APPROVAL= AP YEAR= 1997 NEWMOLECULARENTITY DISCONTINUED
NDA 020624 (pdf not found) INN (DOLASETRON MESYLATE) ANZEMET (VALIDUS PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED