e-Drug3D
1265
ROPIVACAINE
INN
ROPIVACAINE
cas 84057-95-4
CLASS
NERVOUS SYSTEM
ANESTHETIC
BLOCKER
ROUTE (list)
INJECTION
ATC code
N01BB09
PK parameters
VD 41 LITER
Cl 23 LITER / HOUR
PPB 94 PERCENT
t1/2 4.2 HOUR
Solubility
53.8 MILLIGRAM / MILLILITER
TARGET SODIUM CHANNEL
Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A
Sodium channel protein type 1 subunit alpha UNIPROT P35498 SCN1A
Formula:
C17H26N2O
Calculated chemical properties:
MW 274.40
NB_atoms 20
XLogP 3.51
PSA 29.975
NB_HD 1
NB_HA 3
fsp3 0.59
Lipinski(0=no;1=yes) 1
NB_atoms 20
XLogP 3.51
PSA 29.975
NB_HD 1
NB_HA 3
fsp3 0.59
Lipinski(0=no;1=yes) 1
FDA
NDA 020533 (label) INN (ROPIVACAINE HYDROCHLORIDE) NAROPIN (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1996
NDA 078601 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (NAVINTA LLC) APPROVAL= AP YEAR= 2014
NDA 090318 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 090194 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203955 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2016
NDA 205612 (label) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 204636 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2018
NDA 206166 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (INFORLIFE) APPROVAL= AP YEAR= 2018
NDA 207636 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2018
NDA 212808 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (CAPLIN) APPROVAL= TA YEAR= 2020
NDA 214074 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 210102 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2022
NDA 216605 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 206091 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2023
NDA 211907 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2024
NDA 218713 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (KINDOS) APPROVAL= AP YEAR= 2024
NDA 219883 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (ANTHEA PHARMA) APPROVAL= AP YEAR= 2025
NDA 020533 (label) INN (ROPIVACAINE HYDROCHLORIDE) NAROPIN (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1996
NDA 078601 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (NAVINTA LLC) APPROVAL= AP YEAR= 2014
NDA 090318 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 090194 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203955 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2016
NDA 205612 (label) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 204636 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2018
NDA 206166 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (INFORLIFE) APPROVAL= AP YEAR= 2018
NDA 207636 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2018
NDA 212808 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (CAPLIN) APPROVAL= TA YEAR= 2020
NDA 214074 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 210102 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2022
NDA 216605 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 206091 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2023
NDA 211907 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2024
NDA 218713 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (KINDOS) APPROVAL= AP YEAR= 2024
NDA 219883 (pdf not found) INN (ROPIVACAINE HYDROCHLORIDE) ROPIVACAINE HYDROCHLORIDE (ANTHEA PHARMA) APPROVAL= AP YEAR= 2025