e-Drug3D

1260

LEVOMETHADYL ACETATE

DISCONTINUED

INN
LEVOMETHADYL ACETATE

cas 1477-40-3

CLASS

NERVOUS SYSTEM
ANALGESIC
OPIOID AGONIST
NARCOTICS
USAGE IN OPIATE ADDICTION

ROUTE (list)

ORAL

ATC code

N07BC03

PK parameters

VD 1300 LITER (65 KILOGRAM)
Cl 14.3 LITER / HOUR (65 KILOGRAM)
t1/2 62 HOUR

Solubility

> 15 MILLIGRAM / MILLILITER

Target

TARGET MU-TYPE OPIOID RECEPTOR

DrugCentral

Mu-type opioid receptor UNIPROT P35372 OPRM1

Download SDF file

[(3S,6S)-6-dimethylamino-4,4-di(phenyl)heptan-3-yl] acetate

Formula:
C23H31NO2

Calculated chemical properties:

MW 353.49
NB_atoms 26
XLogP 4.65
PSA 25.875
NB_HD 0
NB_HA 3
fsp3 0.43
Lipinski(0=no;1=yes) 1

FDA
NDA 020315 (pdf not found) INN (LEVOMETHADYL ACETATE HYDROCHLORIDE) ORLAAM (ROXANE) APPROVAL= AP YEAR= 1993 NEWMOLECULARENTITY DISCONTINUED