e-Drug3D

125

cas 67-20-9

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
REDUCES BY BACTERIAL FLAVOPROTEINS TO REACTIVE INTERMEDIATES
ALTER BACTERIAL RIBOSOMAL PROTEINS

ROUTE (list)

ORAL INJECTION

PK parameters

Tmax 2.15 HOUR (PMID18429968)
VD 37 LITER (65 KILOGRAM)
Cl 37.8 LITER / HOUR (65 KILOGRAM)
PPB 83 PERCENT
t1/2 0.97 HOUR

MW 238.17
NB_atoms 17
XLogP 0
PSA 115.325
NB_HD 1
NB_HA 8
fsp3 0.12
Lipinski(0=no;1=yes) 1

FDA
NDA 080003 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (ELKINS SINN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080078 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (IVAX SUB TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084085 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (WHITEWORTH TOWN PLSN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 008693 (pdf not found) INN (NITROFURANTOIN) FURADANTIN (PROCTER AND GAMBLE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 009175 (label) INN (NITROFURANTOIN) FURADANTIN (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1953
NDA 012402 (pdf not found) INN (NITROFURANTOIN SODIUM) IVADANTIN (PROCTER AND GAMBLE) APPROVAL= AP YEAR= 1960 DISCONTINUED
NDA 016620 (label) INN (NITROFURANTOIN MACROCRYSTALLINE) MACRODANTIN (ALMATICA) APPROVAL= AP YEAR= 1970
NDA 080017 (pdf not found) INN (NITROFURANTOIN) FURALAN (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 080043 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (SANDOZ) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 085796 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085797 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 084326 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 080447 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (WATSON LABS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070248 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MACROCRYSTALLINE (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 070249 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MACROCRYSTALLINE (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 020064 (label) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) MACROBID (ALMATICA) APPROVAL= AP YEAR= 1991
NDA 073696 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073652 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (IMPAX LABS INC) APPROVAL= AP YEAR= 1993
NDA 073671 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (IMPAX LABS INC) APPROVAL= AP YEAR= 1993
NDA 074336 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (ATHEM) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074967 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 1997
NDA 076648 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (CHARTWELL RX) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 077025 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2004
NDA 076951 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (RANBAXY LABS LTD) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077066 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (SANDOZ) APPROVAL= AP YEAR= 2005
NDA 201679 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 201355 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (STRIDES PHARMA) APPROVAL= AP YEAR= 2013
NDA 201693 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (NOVEL LABS INC) APPROVAL= AP YEAR= 2014
NDA 091095 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 202250 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (WATSON LABS INC) APPROVAL= AP YEAR= 2015
NDA 201722 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2016
NDA 205180 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2016
NDA 207372 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (AMNEAL PHARMS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 205005 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 208516 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (SUNNY) APPROVAL= AP YEAR= 2018
NDA 203233 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (NOVEL LABS INC) APPROVAL= AP YEAR= 2018
NDA 211935 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (ALEMBIC) APPROVAL= AP YEAR= 2021
NDA 211013 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (INVENTIA) APPROVAL= AP YEAR= 2022
NDA 215002 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (ALVOGEN) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 209225 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2023
NDA 212607 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2023
NDA 216385 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2023
NDA 217272 (pdf not found) INN (NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN (MANKIND PHARMA) APPROVAL= AP YEAR= 2023
NDA 217073 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (OMSAV PHARMA) APPROVAL= AP YEAR= 2023
NDA 217357 (pdf not found) INN (NITROFURANTOIN ; NITROFURANTOIN MACROCRYSTALLINE) NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (MANKIND PHARMA) APPROVAL= AP YEAR= 2023
NDA 218346 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (BIOCON PHARMA) APPROVAL= AP YEAR= 2024
NDA 208909 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (APPCO) APPROVAL= AP YEAR= 2025
NDA 219495 (pdf not found) INN (NITROFURANTOIN) NITROFURANTOIN (ANNORA PHARMA) APPROVAL= AP YEAR= 2025