e-Drug3D

1240

PENBUTOLOL

DISCONTINUED

INN
PENBUTOLOL

cas 38363-40-5

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
BETA ADRENERGIC ANTAGONIST

ROUTE (list)

ORAL

PK parameters

PPB 89 PERCENT
t1/2 5 HOUR

Target

TARGET BETA-1 ADRENERGIC RECEPTOR
BETA-2 ADRENERGIC RECEPTOR

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1

Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

Download SDF file

(2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol

Formula:
C18H29NO2

Calculated chemical properties:

MW 291.42
NB_atoms 21
XLogP 3.47
PSA 43.694
NB_HD 2
NB_HA 3
fsp3 0.67
Lipinski(0=no;1=yes) 1

FDA
NDA 018976 (label) INN (PENBUTOLOL SULFATE) LEVATOL (ENDO OPERATIONS) APPROVAL= AP YEAR= 1987 DISCONTINUED