e-Drug3D
1233
CHLORHEXIDINE
INN
CHLORHEXIDINE
cas 55-56-1
CLASS
METABOLISM
ANTIINFECTIVE
ANTI-BACTERIAL
DISINFECTANTS
DESTROYS THE INTEGRITY OF THE CELL MEMBRANE BY INTERACTING WITH THE NEGATIVE CHARGES ASSOCIATED WITH THE CELL WALL AND PLASMA MEMBRANE
ROUTE (list)
TOPICAL DENTAL
ATC code
A01AB03
B05CA02
D08AC02
D09AA12
R02AA05
S01AX09
S02AA09
S03AA04
A01AB53
D08AC52
PK parameters
-
Unknown
Formula:
C22H30Cl2N10
Calculated chemical properties:
MW 505.46
NB_atoms 34
XLogP 3.34
PSA 142.26
NB_HD 10
NB_HA 10
fsp3 0.27
Lipinski(0=no;1=yes) 0
NB_atoms 34
XLogP 3.34
PSA 142.26
NB_HD 10
NB_HA 10
fsp3 0.27
Lipinski(0=no;1=yes) 0
FDA
NDA 019490 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (KENDALL IL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017768 (label) INN (CHLORHEXIDINE GLUCONATE) HIBICLENS (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1976
NDA 018300 (label) INN (CHLORHEXIDINE GLUCONATE) HIBISTAT (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1980
NDA 018423 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) HIBICLENS (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 019125 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1984
NDA 019127 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1984
NDA 019421 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 019422 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1985
NDA 019028 (label) INN (CHLORHEXIDINE GLUCONATE) PERIDEX (3M) APPROVAL= AP YEAR= 1986
NDA 019258 (label) INN (CHLORHEXIDINE GLUCONATE) CIDA-STAT (ECOLAB) APPROVAL= AP YEAR= 1986
NDA 070104 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) STERI-STAT (MATRIX MEDCL) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071419 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) BRIAN CARE (SOAPCO) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 019793 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PHARMASEAL SCRUB CARE (CAREFUSION 2200) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 019822 (label) INN (CHLORHEXIDINE GLUCONATE) BIOSCRUB (GRIFFEN) APPROVAL= AP YEAR= 1989
NDA 072525 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BECTON DICKINSON) APPROVAL= AP YEAR= 1989
NDA 072255 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) MICRODERM (J AND J) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 072295 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) MICRODERM (J AND J) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 072292 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PREVACARE R (J AND J) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073695 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PERIOGARD (COLGATE PALMOLIVE CO) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074291 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (LYNE) APPROVAL= AP YEAR= 1995
NDA 074522 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (PHARM ASSOC) APPROVAL= AP YEAR= 1995
NDA 074356 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020111 (label) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BAJAJ) APPROVAL= AP YEAR= 1997
NDA 020774 (label) INN (CHLORHEXIDINE GLUCONATE) PERIOCHIP (DEXCEL PHARMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 020832 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) CHLORAPREP ONE-STEP (BECTON DICKINSON CO) APPROVAL= AP YEAR= 2000
NDA 073416 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) E-Z SCRUB (BECTON DICKINSON) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075561 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BAJAJ) APPROVAL= AP YEAR= 2000
NDA 021074 (label) INN (ALCOHOL ; CHLORHEXIDINE GLUCONATE) AVAGARD (3M) APPROVAL= AP YEAR= 2001
NDA 021555 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) CHLORAPREP ONE-STEP SEPP (BECTON DICKINSON CO) APPROVAL= AP YEAR= 2002
NDA 075006 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2004
NDA 021524 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) PREVANTICS SWAB (PROF DSPLS) APPROVAL= AP YEAR= 2005
NDA 021669 (label) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (SAGE PRODS) APPROVAL= AP YEAR= 2005
NDA 076434 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PAROEX (SUNSTAR AMERICAS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077789 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2009
NDA 203212 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PERIOGARD (COLGATE-PALMOLIVE CO) APPROVAL= AP YEAR= 2016
NDA 207964 (label) INN (CHLORHEXIDINE GLUCONATE) READYPREP CHG (MEDLINE INDUSTRIES) APPROVAL= AP YEAR= 2018
NDA 208288 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) SOLUPREP S (3M HEALTH CARE) APPROVAL= AP YEAR= 2018
NDA 019490 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (KENDALL IL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017768 (label) INN (CHLORHEXIDINE GLUCONATE) HIBICLENS (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1976
NDA 018300 (label) INN (CHLORHEXIDINE GLUCONATE) HIBISTAT (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1980
NDA 018423 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) HIBICLENS (MOLNLYCKE HLTH) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 019125 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1984
NDA 019127 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1984
NDA 019421 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 019422 (label) INN (CHLORHEXIDINE GLUCONATE) EXIDINE (XTTRIUM) APPROVAL= AP YEAR= 1985
NDA 019028 (label) INN (CHLORHEXIDINE GLUCONATE) PERIDEX (3M) APPROVAL= AP YEAR= 1986
NDA 019258 (label) INN (CHLORHEXIDINE GLUCONATE) CIDA-STAT (ECOLAB) APPROVAL= AP YEAR= 1986
NDA 070104 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) STERI-STAT (MATRIX MEDCL) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 071419 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) BRIAN CARE (SOAPCO) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 019793 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PHARMASEAL SCRUB CARE (CAREFUSION 2200) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 019822 (label) INN (CHLORHEXIDINE GLUCONATE) BIOSCRUB (GRIFFEN) APPROVAL= AP YEAR= 1989
NDA 072525 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BECTON DICKINSON) APPROVAL= AP YEAR= 1989
NDA 072255 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) MICRODERM (J AND J) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 072295 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) MICRODERM (J AND J) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 072292 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PREVACARE R (J AND J) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073695 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PERIOGARD (COLGATE PALMOLIVE CO) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074291 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (LYNE) APPROVAL= AP YEAR= 1995
NDA 074522 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (PHARM ASSOC) APPROVAL= AP YEAR= 1995
NDA 074356 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020111 (label) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BAJAJ) APPROVAL= AP YEAR= 1997
NDA 020774 (label) INN (CHLORHEXIDINE GLUCONATE) PERIOCHIP (DEXCEL PHARMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 020832 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) CHLORAPREP ONE-STEP (BECTON DICKINSON CO) APPROVAL= AP YEAR= 2000
NDA 073416 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) E-Z SCRUB (BECTON DICKINSON) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075561 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (BAJAJ) APPROVAL= AP YEAR= 2000
NDA 021074 (label) INN (ALCOHOL ; CHLORHEXIDINE GLUCONATE) AVAGARD (3M) APPROVAL= AP YEAR= 2001
NDA 021555 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) CHLORAPREP ONE-STEP SEPP (BECTON DICKINSON CO) APPROVAL= AP YEAR= 2002
NDA 075006 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2004
NDA 021524 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) PREVANTICS SWAB (PROF DSPLS) APPROVAL= AP YEAR= 2005
NDA 021669 (label) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (SAGE PRODS) APPROVAL= AP YEAR= 2005
NDA 076434 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PAROEX (SUNSTAR AMERICAS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077789 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) CHLORHEXIDINE GLUCONATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2009
NDA 203212 (pdf not found) INN (CHLORHEXIDINE GLUCONATE) PERIOGARD (COLGATE-PALMOLIVE CO) APPROVAL= AP YEAR= 2016
NDA 207964 (label) INN (CHLORHEXIDINE GLUCONATE) READYPREP CHG (MEDLINE INDUSTRIES) APPROVAL= AP YEAR= 2018
NDA 208288 (label) INN (CHLORHEXIDINE GLUCONATE ; ISOPROPYL ALCOHOL) SOLUPREP S (3M HEALTH CARE) APPROVAL= AP YEAR= 2018