e-Drug3D
1231
CLEMASTINE
INN
CLEMASTINE
cas 15686-51-8
CLASS
DERMATOLOGICALS
ANTIHISTAMINE
ANTI-ALLERGIC AGENTS
ANTIPRURITICS
HISTAMINE H1 RECEPTOR ANTAGONIST
ANTICHOLINERGIC
ROUTE (list)
ORAL
PK parameters
Tmax 3.5 HOUR
TARGET HISTAMINE H1 RECEPTOR
Histamine H1 receptor UNIPROT P35367 HRH1
Formula:
C21H26ClNO
Calculated chemical properties:
MW 343.88
NB_atoms 24
XLogP 5.10
PSA 14.262
NB_HD 0
NB_HA 2
fsp3 0.43
Lipinski(0=no;1=yes) 0
NB_atoms 24
XLogP 5.10
PSA 14.262
NB_HD 0
NB_HA 2
fsp3 0.43
Lipinski(0=no;1=yes) 0
FDA
NDA 017661 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST (NOVARTIS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 018298 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-D (NOVARTIS) APPROVAL= AP YEAR= 1982 DISCONTINUED OBSOLETE
NDA 018675 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST (NOVARTIS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020925 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-1 (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073095 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (TEVA PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073282 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (ANI PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073283 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (GENUS) APPROVAL= AP YEAR= 1992
NDA 073458 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (PLD ACQUISITIONS LLC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 073459 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (OMNIVIUM PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074075 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 073399 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (GENUS) APPROVAL= AP YEAR= 1994
NDA 074512 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (L PERRIGO CO) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020640 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-D (NOVARTIS) APPROVAL= AP YEAR= 1996 DISCONTINUED OBSOLETE
NDA 074884 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (NEW HEIGHTSRX) APPROVAL= AP YEAR= 1997
NDA 074863 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075703 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021082 (pdf not found) INN (ACETAMINOPHEN ; CLEMASTINE FUMARATE ; PSEUDOEPHEDRINE HYDROCHLORIDE) TAVIST ALLERGY/SINUS/HEADACHE (NOVARTIS) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 017661 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST (NOVARTIS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 018298 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-D (NOVARTIS) APPROVAL= AP YEAR= 1982 DISCONTINUED OBSOLETE
NDA 018675 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST (NOVARTIS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020925 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-1 (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073095 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (TEVA PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073282 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (ANI PHARMS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073283 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (GENUS) APPROVAL= AP YEAR= 1992
NDA 073458 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (PLD ACQUISITIONS LLC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 073459 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (OMNIVIUM PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074075 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 073399 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (GENUS) APPROVAL= AP YEAR= 1994
NDA 074512 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (L PERRIGO CO) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020640 (pdf not found) INN (CLEMASTINE FUMARATE) TAVIST-D (NOVARTIS) APPROVAL= AP YEAR= 1996 DISCONTINUED OBSOLETE
NDA 074884 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (NEW HEIGHTSRX) APPROVAL= AP YEAR= 1997
NDA 074863 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075703 (pdf not found) INN (CLEMASTINE FUMARATE) CLEMASTINE FUMARATE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021082 (pdf not found) INN (ACETAMINOPHEN ; CLEMASTINE FUMARATE ; PSEUDOEPHEDRINE HYDROCHLORIDE) TAVIST ALLERGY/SINUS/HEADACHE (NOVARTIS) APPROVAL= AP YEAR= 2001 DISCONTINUED