e-Drug3D

1230

AZATADINE

DISCONTINUED

INN
AZATADINE

cas 3964-81-6

CLASS

RESPIRATORY
ANTIHISTAMINE
HISTAMINE H1 RECEPTOR ANTAGONIST
ANTICHOLINERGIC
ANTISEROTONIN
ANTIANAPHYLACTIC ACTIVITY PMID21737359

ROUTE (list)

ORAL

ATC code

R06AX09

PK parameters

Target

TARGET HISTAMINE H1 RECEPTOR

DrugCentral

Histamine H1 receptor UNIPROT P35367 HRH1

Download SDF file

5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-

Formula:
C20H22N2

Calculated chemical properties:

MW 290.40
NB_atoms 22
XLogP 3.71
PSA 13.177
NB_HD 0
NB_HA 2
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 017601 (pdf not found) INN (AZATADINE MALEATE) OPTIMINE (SCHERING) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 018506 (pdf not found) INN (AZATADINE MALEATE ; PSEUDOEPHEDRINE SULFATE) TRINALIN (SCHERING) APPROVAL= AP YEAR= 1982 DISCONTINUED