e-Drug3D

1220

CARPHENAZINE

DISCONTINUED

INN
CARPHENAZINE

cas 2622-30-2

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
DOPAMINE RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

ATC code

PK parameters

Target

TARGET D(1A) DOPAMINE RECEPTOR
D(1B) DOPAMINE RECEPTOR
D(2) DOPAMINE RECEPTOR

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A

Download SDF file

1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]propan-1-one

Formula:
C24H31N3O2S

Calculated chemical properties:

MW 425.59
NB_atoms 30
XLogP 3.88
PSA 48.159
NB_HD 1
NB_HA 5
fsp3 0.46
Lipinski(0=no;1=yes) 1

FDA
NDA 012768 (pdf not found) INN (CARPHENAZINE MALEATE) PROKETAZINE (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 014173 (pdf not found) INN (CARPHENAZINE MALEATE) PROKETAZINE (WYETH AYERST) APPROVAL= AP YEAR= 1963 DISCONTINUED