e-Drug3D

1214

cas 86-13-5

CLASS

NERVOUS SYSTEM
ANTIPARKINSONIAN
ANTIDYSKINETICS
MUSCARINIC ANTAGONISTS
DOPAMINE TRANSPORTER LIGANDS (PMID18786172)

ROUTE (list)

ORAL INJECTION

PK parameters

TARGET DOPAMINE TRANSPORTER
MUSCARINIC ACETYLCHOLINE RECEPTOR

PDB
6F6S (CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH BENZTROPINE)

Ligand code = CXQ (link to the list of PDB complexes)

Download experimental 3D coordinates of CXQ with added hydrogens

MW 307.42
NB_atoms 23
XLogP 4.42
PSA 8.407
NB_HD 0
NB_HA 2
fsp3 0.43
Lipinski(0=no;1=yes) 1

FDA
NDA 088510 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088511 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088514 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089211 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089212 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089213 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009193 (pdf not found) INN (BENZTROPINE MESYLATE) COGENTIN (MERCK) APPROVAL= AP YEAR= 1954 DISCONTINUED
NDA 012015 (label) INN (BENZTROPINE MESYLATE) COGENTIN (EPIC PHARMA LLC) APPROVAL= TA YEAR= 1959
NDA 088877 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (LANNETT CO INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088894 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (LANNETT CO INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088895 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (LANNETT CO INC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089058 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PLIVA) APPROVAL= AP YEAR= 1988
NDA 089059 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PLIVA) APPROVAL= AP YEAR= 1988
NDA 089060 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PLIVA) APPROVAL= AP YEAR= 1988
NDA 072264 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1989
NDA 072265 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1989
NDA 072266 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1989
NDA 081264 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (CHARTWELL RX) APPROVAL= AP YEAR= 1992 DISCONTINUED OBSOLETE
NDA 081265 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (CHARTWELL RX) APPROVAL= AP YEAR= 1992
NDA 040103 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (AIPING PHARM INC) APPROVAL= AP YEAR= 1996
NDA 040715 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PH HEALTH) APPROVAL= AP YEAR= 2007
NDA 040738 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (VINTAGE) APPROVAL= AP YEAR= 2007 OBSOLETE
NDA 040742 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (VINTAGE) APPROVAL= AP YEAR= 2007 OBSOLETE
NDA 040699 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PROSAM LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED OBSOLETE
NDA 040705 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (PROSAM LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED OBSOLETE
NDA 040706 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (OXFORD PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090233 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2009
NDA 090287 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2009
NDA 090294 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091152 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (LUITPOLD) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090168 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (LEADING) APPROVAL= AP YEAR= 2012
NDA 091525 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (NAVINTA LLC) APPROVAL= AP YEAR= 2013
NDA 204713 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (NUVO PHARM) APPROVAL= AP YEAR= 2015
NDA 209442 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (HIKMA) APPROVAL= AP YEAR= 2021
NDA 212694 (pdf not found) INN (BENZTROPINE MESYLATE) BENZTROPINE MESYLATE (QUAGEN) APPROVAL= AP YEAR= 2025