e-Drug3D

1207

cas 51-41-2

CLASS

CARDIOVASCULAR
ADRENERGIC RECEPTOR AGONIST
SYMPATHOMIMETICS
VASOCONSTRICTOR AGENTS
PERIPHERAL VASOCONSTRICTOR (ALPHA-ADRENERGIC ACTION) AND AS AN INOTROPIC STIMULATOR OF THE HEART AND DILATOR OF CORONARY ARTERIES (BETA-ADRENERGIC ACTION)

ROUTE (list)

INJECTION INTRAVENOUS

PK parameters

TARGET ADRENERGIC RECEPTORS

PDB
3HCD (CRYSTAL STRUCTURE OF HPNMT IN COMPLEX WITH NORADRENALINE AND ADOHCY)

Ligand code = LNR (link to the list of PDB complexes)

Download experimental 3D coordinates of LNR with added hydrogens

MW 169.18
NB_atoms 12
XLogP 0.09
PSA 87.389
NB_HD 5
NB_HA 4
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
NDA 007513 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) LEVOPHED (HOSPIRA) APPROVAL= AP YEAR= 1950
NDA 008592 (pdf not found) INN (NOREPINEPHRINE BITARTRATE ; PROCAINE HYDROCHLORIDE ; PROPOXYCAINE HYDROCHLORIDE) RAVOCAINE AND NOVOCAIN W/ LEVOPHED (EASTMAN KODAK) APPROVAL= AP YEAR= 1952 DISCONTINUED
NDA 040455 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (MEITHEAL) APPROVAL= AP YEAR= 2003
NDA 040462 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (HIKMA) APPROVAL= AP YEAR= 2003
NDA 040522 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (METRICS PHARM) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 040859 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2012
NDA 203662 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (HIKMA) APPROVAL= AP YEAR= 2018
NDA 210839 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (AMNEAL) APPROVAL= AP YEAR= 2018
NDA 211242 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2018
NDA 211359 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (SANDOZ) APPROVAL= AP YEAR= 2018
NDA 211382 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2020
NDA 211980 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (SUN PHARM) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214313 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2021
NDA 214323 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (GLAND) APPROVAL= AP YEAR= 2021
NDA 214455 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (BRECKENRIDGE) APPROVAL= AP YEAR= 2021
NDA 214628 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDE (LONG GROVE PHARMS) APPROVAL= AP YEAR= 2022
NDA 215700 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDE (INFORLIFE) APPROVAL= AP YEAR= 2022
NDA 216341 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 217575 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (CAPLIN) APPROVAL= AP YEAR= 2023
NDA 218758 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (RISING) APPROVAL= AP YEAR= 2024
NDA 219163 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (ASPIRO) APPROVAL= AP YEAR= 2025
NDA 219443 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE (BIOCON PHARMA) APPROVAL= AP YEAR= 2025
NDA 219692 (pdf not found) INN (NOREPINEPHRINE BITARTRATE) NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE (SAGENT) APPROVAL= AP YEAR= 2025