e-Drug3D

1206

METHANTHELINE

DISCONTINUED

INN
METHANTHELINE

cas 5818-17-7

CLASS

METABOLISM
ANTISPASMODIC
CHOLINERGIC RECEPTOR ANTAGONIST
TREATMENT OF OVERACTIVE BLADDER SYNDROME, HYPERSALIVATION AND HYPERHIDROSIS

ROUTE (list)

ORAL

ATC code

A03AB07

PK parameters

t1/2 2 HOUR

Target

TARGET MUSCARINIC ACETYLCHOLINE RECEPTOR M1

Muscarinic acetylcholine receptor UNIPROT P08172 CHRM2

Download SDF file

diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium

Formula:
C21H26NO3

Calculated chemical properties:

MW 340.43
NB_atoms 25
XLogP 3.95
PSA 32.485
NB_HD 0
NB_HA 3
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 007390 (pdf not found) INN (METHANTHELINE BROMIDE) BANTHINE (SHIRE) APPROVAL= AP YEAR= 1951 NEWMOLECULARENTITY DISCONTINUED