e-Drug3D

1201

cas 80012-43-7

CLASS

RESPIRATORY SYSTEM
ANTIHISTAMINE
ANTIALLERGIC
HISTAMINE H1 RECEPTOR ANTAGONISTS

ROUTE (list)

OPHTHALMIC

PK parameters

Cl 56 LITER / HOUR
PPB 64 PERCENT
t1/2 12 HOUR

MW 249.31
NB_atoms 19
XLogP 2.47
PSA 38.126
NB_HD 2
NB_HA 3
fsp3 0.19
Lipinski(0=no;1=yes) 1

FDA
NDA 021565 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) ELESTAT (ALLERGAN) APPROVAL= AP YEAR= 2003 NEWMOLECULARENTITY DISCONTINUED
NDA 090919 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2011
NDA 090951 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2011
NDA 090870 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (RENOVA PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090950 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (SANDOZ) APPROVAL= TA YEAR= 2011
NDA 091626 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (SUN PHARM INDS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 203384 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 204055 (pdf not found) INN (EPINASTINE HYDROCHLORIDE) EPINASTINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2017 DISCONTINUED