e-Drug3D

1193

LOMEFLOXACIN

DISCONTINUED

INN
LOMEFLOXACIN

cas 98079-51-7

CLASS

ANTIBACTERIAL
ANTIINFECTIVE
INHIBITOR

ROUTE (list)

ORAL

PK parameters

F 97 PERCENT
Cl 8.7 LITER / HOUR
PPB 10 PERCENT
t1/2 7.75 HOUR

Solubility

SLIGHTLY SOLUBLE IN WATER

Target

TARGET DNA GYRASE
DNA TOPOISOMERASE

DNA gyrase UNIPROT P0AES4 gyrA

Download SDF file

1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

Formula:
C17H19F2N3O3

Calculated chemical properties:

MW 350.34
NB_atoms 25
XLogP 0.46
PSA 73.184
NB_HD 1
NB_HA 6
fsp3 0.41
Lipinski(0=no;1=yes) 1

FDA
NDA 020013 (pdf not found) INN (LOMEFLOXACIN HYDROCHLORIDE) MAXAQUIN (PHARMACIA) APPROVAL= AP YEAR= 1992 NEWMOLECULARENTITY DISCONTINUED