e-Drug3D

1180

CARTEOLOL

INN
CARTEOLOL

cas 51781-06-7

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANTIANGINAL
ADRENERGIC (BETA) BLOCKER
ANTI-ARRHYTHMIA AGENTS
ANTIHYPERTENSIVE AGENTS
SYMPATHOLYTICS
LOWERING INTRAOCULAR PRESSURE AND MAY BE USED IN PATIENTS WITH CHRONIC OPEN-ANGLE GLAUCOMA AND INTRAOCULAR HYPERTENSION.

ROUTE (list)

ORAL OPHTHALMIC

ATC code

C07AA15
S01ED05
S01ED55

PK parameters

Solubility

SOLUBLE IN WATER

Target

TARGET BETA-1 ADRENERGIC RECEPTOR
BETA-2 ADRENERGIC RECEPTOR

DrugCentral

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1

Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

Download SDF file

5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one

Formula:
C16H24N2O3

Calculated chemical properties:

MW 292.37
NB_atoms 21
XLogP 1.70
PSA 74.599
NB_HD 3
NB_HA 5
fsp3 0.56
Lipinski(0=no;1=yes) 1

FDA
NDA 019204 (pdf not found) INN (CARTEOLOL HYDROCHLORIDE) CARTROL (ABBVIE) APPROVAL= AP YEAR= 1988 NEWMOLECULARENTITY DISCONTINUED
NDA 019972 (pdf not found) INN (CARTEOLOL HYDROCHLORIDE) OCUPRESS (NOVARTIS) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 075476 (pdf not found) INN (CARTEOLOL HYDROCHLORIDE) CARTEOLOL HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2000
NDA 075546 (pdf not found) INN (CARTEOLOL HYDROCHLORIDE) CARTEOLOL HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 076097 (pdf not found) INN (CARTEOLOL HYDROCHLORIDE) CARTEOLOL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2002 DISCONTINUED