e-Drug3D

118

cas 306-40-1

CLASS

METABOLISM
ULTRA SHORT-ACTING NEUROMUSCULAR DEPOLARIZING AGENTS
SKELETAL MUSCLE RELAXANTS
ADJUNCT TO GENERAL ANESTHESIA

ROUTE (list)

INJECTION INTRAMUSCULAR INTRAVENOUS

PK parameters

VD 0.14 LITER (65 KILOGRAM)
Cl 250.2 LITER / HOUR
t1/2 0.07 HOUR (PMID14564614)

TARGET ACETYLCHOLINE RECEPTOR

PDB
2HA6 (CRYSTAL STRUCTURE OF MUTANT S203A OF MOUSE ACETYLCHOLINESTERASE COMPLEXED WITH SUCCINYLCHOLINE)

Ligand code = SCK (link to the list of PDB complexes)

Download experimental 3D coordinates of SCK with added hydrogens

MW 290.40
NB_atoms 20
XLogP 0.27
PSA 44.996
NB_HD 0
NB_HA 4
fsp3 0.86
Lipinski(0=no;1=yes) 1

FDA
NDA 085400 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 008453 (label) INN (SUCCINYLCHOLINE CHLORIDE) ANECTINE (SANDOZ) APPROVAL= AP YEAR= 1952
NDA 008845 (label) INN (SUCCINYLCHOLINE CHLORIDE) QUELICIN PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1953
NDA 008847 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCOSTRIN (APOTHECON) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 080997 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (ORGANON USA INC) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 209467 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 210231 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (AMRING PHARMS) APPROVAL= AP YEAR= 2018
NDA 211432 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2018
NDA 210698 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (DR REDDYS) APPROVAL= AP YEAR= 2019
NDA 212638 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (BRECKENRIDGE) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211589 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2020
NDA 211625 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (UMEDICA) APPROVAL= AP YEAR= 2020
NDA 213229 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 213432 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (AMPHASTAR PHARMS INC) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213705 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213810 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (ASPIRO) APPROVAL= AP YEAR= 2020
NDA 214246 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (GLAND) APPROVAL= AP YEAR= 2020
NDA 214308 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (ADAPTIS) APPROVAL= AP YEAR= 2020
NDA 211346 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2020
NDA 213552 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (NEXUS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 214491 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (DEVA HOLDING AS) APPROVAL= AP YEAR= 2020
NDA 214879 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (MICRO LABS) APPROVAL= AP YEAR= 2020
NDA 215022 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2021
NDA 214514 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (MEITHEAL) APPROVAL= AP YEAR= 2021
NDA 215143 (label) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (HIKMA) APPROVAL= AP YEAR= 2021
NDA 216003 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (BE PHARMS) APPROVAL= AP YEAR= 2022
NDA 216127 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (MANKIND PHARMA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 217808 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 218467 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (DR REDDYS) APPROVAL= AP YEAR= 2024
NDA 217873 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (STERISCIENCE) APPROVAL= AP YEAR= 2024
NDA 218878 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2024
NDA 217884 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2025
NDA 217885 (pdf not found) INN (SUCCINYLCHOLINE CHLORIDE) SUCCINYLCHOLINE CHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2025