e-Drug3D

1166

cas 27220-47-9

CLASS

DERMATOLOGICALS
ANTIFUNGAL
INHIBITORS

ROUTE (list)

TOPICAL

PK parameters

Tmax 6.8 HOUR

TARGET CYTOCHROME P450

PDB
6B5V (STRUCTURE OF TRPV5 IN COMPLEX WITH ECONAZOLE)

Ligand code = ECL (link to the list of PDB complexes)

Download experimental 3D coordinates of ECL with added hydrogens

MW 381.67
NB_atoms 24
XLogP 5.80
PSA 22.015
NB_HD 0
NB_HA 3
fsp3 0.17
Lipinski(0=no;1=yes) 0

FDA
NDA 018751 (label) INN (ECONAZOLE NITRATE) SPECTAZOLE (ALVOGEN) APPROVAL= AP YEAR= 1982 NEWMOLECULARENTITY DISCONTINUED
NDA 076005 (label) INN (ECONAZOLE NITRATE) ECONAZOLE NITRATE (TARO) APPROVAL= AP YEAR= 2002
NDA 076075 (label) INN (ECONAZOLE NITRATE) ECONAZOLE NITRATE (CHARTWELL RX) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076479 (pdf not found) INN (ECONAZOLE NITRATE) ECONAZOLE NITRATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2004
NDA 076574 (pdf not found) INN (ECONAZOLE NITRATE) ECONAZOLE NITRATE (ENCUBE) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 205175 (label) INN (ECONAZOLE NITRATE) ECOZA (RESILIA PHARMS) APPROVAL= AP YEAR= 2013
NDA 210364 (pdf not found) INN (ECONAZOLE NITRATE) ECONAZOLE NITRATE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2018 DISCONTINUED