e-Drug3D

1158

OXPRENOLOL

DISCONTINUED

INN
OXPRENOLOL

cas 6452-71-7

CLASS

CARDIOVASCULAR
CORONARY VASODILATOR
ADRENERGIC BETA ANTAGONISTS
ANTI-ARRHYTHMIA AGENTS
ANTI-ANXIETY AGENTS
ANTIHYPERTENSIVE AGENTS
SYMPATHOLYTICS

ROUTE (list)

ORAL

PK parameters

F 46.5 PERCENT
Tmax 1.5 HOUR
VD 180 LITER
Cl 120 LITER / HOUR
t1/2 1.5 HOUR

Target

TARGET BETA-1 ADRENERGIC RECEPTOR
BETA-2 ADRENERGIC RECEPTOR

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1

Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

Download SDF file

1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol

Formula:
C15H23NO3

Calculated chemical properties:

MW 265.34
NB_atoms 19
XLogP 1.99
PSA 55.497
NB_HD 2
NB_HA 4
fsp3 0.47
Lipinski(0=no;1=yes) 1

FDA
NDA 018166 (pdf not found) INN (OXPRENOLOL HYDROCHLORIDE) TRASICOR (NOVARTIS) APPROVAL= - YEAR= 0 DISCONTINUED