e-Drug3D
1147
MOLINDONE
INN
MOLINDONE
cas 7416-34-4
CLASS
NERVOUS SYSTEM
ANTIPSYCHOTIC
MANAGEMENT OF SCHIZOPHRENIA
DOPAMINE RECEPTOR ANTAGONIST
ROUTE (list)
ORAL
ATC code
N05AE02
PK parameters
Tmax 1.5 HOUR
t1/2 2 HOUR
Solubility
FREELY SOLUBLE IN WATER
TARGET D(2) DOPAMINE RECEPTOR
D(2) dopamine receptor UNIPROT P14416 DRD2
5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A
Formula:
C16H24N2O2
Calculated chemical properties:
MW 276.37
NB_atoms 20
XLogP 1.96
PSA 45.341
NB_HD 1
NB_HA 4
fsp3 0.69
Lipinski(0=no;1=yes) 1
NB_atoms 20
XLogP 1.96
PSA 45.341
NB_HD 1
NB_HA 4
fsp3 0.69
Lipinski(0=no;1=yes) 1
FDA
NDA 017111 (label) INN (MOLINDONE HYDROCHLORIDE) MOBAN (CHARTWELL RX) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017938 (pdf not found) INN (MOLINDONE HYDROCHLORIDE) MOBAN (ENDO PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 090453 (pdf not found) INN (MOLINDONE HYDROCHLORIDE) MOLINDONE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2015
NDA 017111 (label) INN (MOLINDONE HYDROCHLORIDE) MOBAN (CHARTWELL RX) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017938 (pdf not found) INN (MOLINDONE HYDROCHLORIDE) MOBAN (ENDO PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 090453 (pdf not found) INN (MOLINDONE HYDROCHLORIDE) MOLINDONE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2015