e-Drug3D
1137
DOXAPRAM
INN
DOXAPRAM
cas 309-29-5
CLASS
RESPIRATORY SYSTEM
RESPIRATORY STIMULANT
CENTRAL NERVOUS SYSTEM STIMULANTS
ROUTE (list)
INJECTION
ATC code
R07AB01
PK parameters
VD 78 LITER (65 KILOGRAM)
Cl 20 LITER / HOUR (65 KILOGRAM)
t1/2 4.1 HOUR
Solubility
SPARINGLY SOLUBLE IN WATER
-
Potassium channel subfamily K member 3 UNIPROT O14649 KCNK3
Potassium channel subfamily K member 9 UNIPROT Q9NPC2 KCNK9
Formula:
C24H30N2O2
Calculated chemical properties:
MW 378.50
NB_atoms 28
XLogP 3.17
PSA 33.858
NB_HD 0
NB_HA 4
fsp3 0.46
Lipinski(0=no;1=yes) 1
NB_atoms 28
XLogP 3.17
PSA 33.858
NB_HD 0
NB_HA 4
fsp3 0.46
Lipinski(0=no;1=yes) 1
FDA
NDA 014879 (label) INN (DOXAPRAM HYDROCHLORIDE) DOPRAM (HIKMA) APPROVAL= AP YEAR= 1965
NDA 073529 (pdf not found) INN (DOXAPRAM HYDROCHLORIDE) DOXAPRAM HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 076266 (pdf not found) INN (DOXAPRAM HYDROCHLORIDE) DOXAPRAM HYDROCHLORIDE (CHARTWELL INJECTABLE) APPROVAL= AP YEAR= 2003
NDA 014879 (label) INN (DOXAPRAM HYDROCHLORIDE) DOPRAM (HIKMA) APPROVAL= AP YEAR= 1965
NDA 073529 (pdf not found) INN (DOXAPRAM HYDROCHLORIDE) DOXAPRAM HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 076266 (pdf not found) INN (DOXAPRAM HYDROCHLORIDE) DOXAPRAM HYDROCHLORIDE (CHARTWELL INJECTABLE) APPROVAL= AP YEAR= 2003