e-Drug3D

1132

OXYPHENBUTAZONE

DISCONTINUED

INN
OXYPHENBUTAZONE

cas 129-20-4

CLASS

MUSCULO-SKELETAL
ANTIRHEUMATIC
ANTIINFLAMMATORY
NSAID
INHIBITOR

ROUTE (list)

ORAL

ATC code

M01AA03
M02AA04
S01BC02

PK parameters

Target

PDB
2BXB (HUMAN SERUM ALBUMIN COMPLEXED WITH OXYPHENBUTAZONE)

Ligand code = OPB_2BXB (link to the list of PDB complexes)

Download experimental 3D coordinates of OPB_2BXB with added hydrogens

DrugCentral

Cyclooxygenase UNIPROT P23219 PTGS1

Download SDF file

4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione

Formula:
C19H20N2O3

Calculated chemical properties:

MW 324.37
NB_atoms 24
XLogP 3.49
PSA 61.258
NB_HD 1
NB_HA 5
fsp3 0.26
Lipinski(0=no;1=yes) 1

FDA
NDA 088399 (pdf not found) INN (OXYPHENBUTAZONE) OXYPHENBUTAZONE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012542 (pdf not found) INN (OXYPHENBUTAZONE) TANDEARIL (NOVARTIS) APPROVAL= AP YEAR= 1960 DISCONTINUED