e-Drug3D
1131
METHYCLOTHIAZIDE
DISCONTINUED
INN
METHYCLOTHIAZIDE
cas 135-07-9
CLASS
CARDIOVASCULAR
DIURETIC THIAZIDE
ANTIHYPERTENSIVE
SODIUM CHLORIDE SYMPORTER INHIBITORS
ROUTE (list)
ORAL
PK parameters
Solubility
VERY SLIGHTLY SOLUBLE IN WATER
TARGET SODIUM CHLORIDE SYMPORTER
Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3
Formula:
C9H11Cl2N3O4S2
Calculated chemical properties:
MW 360.25
NB_atoms 20
XLogP 0.60
PSA 107.057
NB_HD 3
NB_HA 7
fsp3 0.33
Lipinski(0=no;1=yes) 1
NB_atoms 20
XLogP 0.60
PSA 107.057
NB_HD 3
NB_HA 7
fsp3 0.33
Lipinski(0=no;1=yes) 1
FDA
NDA 016047 (pdf not found) INN (METHYCLOTHIAZIDE ; PARGYLINE HYDROCHLORIDE) EUTRON (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085476 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085487 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087671 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088452 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) METHYCLOTHIAZIDE AND DESERPIDINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088486 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) METHYCLOTHIAZIDE AND DESERPIDINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088745 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012524 (pdf not found) INN (METHYCLOTHIAZIDE) ENDURON (ABBVIE) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 012775 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) ENDURONYL (ABBOTT) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 012708 (pdf not found) INN (METHYCLOTHIAZIDE ; RESERPINE) DIUTENSEN-R (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017364 (pdf not found) INN (METHYCLOTHIAZIDE) AQUATENSEN (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 087672 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087786 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (IVAX PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087913 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (IVAX PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088724 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088750 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 089135 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089136 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089835 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089837 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 016047 (pdf not found) INN (METHYCLOTHIAZIDE ; PARGYLINE HYDROCHLORIDE) EUTRON (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085476 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085487 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087671 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088452 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) METHYCLOTHIAZIDE AND DESERPIDINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088486 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) METHYCLOTHIAZIDE AND DESERPIDINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088745 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012524 (pdf not found) INN (METHYCLOTHIAZIDE) ENDURON (ABBVIE) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 012775 (pdf not found) INN (DESERPIDINE ; METHYCLOTHIAZIDE) ENDURONYL (ABBOTT) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 012708 (pdf not found) INN (METHYCLOTHIAZIDE ; RESERPINE) DIUTENSEN-R (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017364 (pdf not found) INN (METHYCLOTHIAZIDE) AQUATENSEN (MEDPOINTE PHARM HLC) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 087672 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087786 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (IVAX PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087913 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (IVAX PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088724 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088750 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (WATSON LABS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 089135 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089136 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089835 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089837 (pdf not found) INN (METHYCLOTHIAZIDE) METHYCLOTHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED