e-Drug3D
1115
TRIMEPRAZINE
DISCONTINUED
INN
TRIMEPRAZINE
cas 84-96-8
CLASS
RESPIRATORY SYSTEM
PHENOTHIAZINE
ANTIHISTAMINIC
NEUROLEPTIC
SEDATIVE
ANTIMUSCARINIC
AMINE BINDING GPCR RECEPTOR ANTAGONIST
ROUTE (list)
ORAL
ATC code
R06AD01
PK parameters
F 80 PERCENT
PPB 90 PERCENT
TARGET HISTAMINE H1 RECEPTOR
Histamine H1 receptor UNIPROT P35367 HRH1
Formula:
C18H22N2S
Calculated chemical properties:
MW 298.45
NB_atoms 21
XLogP 4.49
PSA 7.506
NB_HD 0
NB_HA 2
fsp3 0.33
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 4.49
PSA 7.506
NB_HD 0
NB_HA 2
fsp3 0.33
Lipinski(0=no;1=yes) 1
FDA
NDA 011316 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TEMARIL (ALLERGAN HERBERT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085015 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TRIMEPRAZINE TARTRATE (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088285 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TRIMEPRAZINE TARTRATE (MORTON GROVE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011316 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TEMARIL (ALLERGAN HERBERT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085015 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TRIMEPRAZINE TARTRATE (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088285 (pdf not found) INN (TRIMEPRAZINE TARTRATE) TRIMEPRAZINE TARTRATE (MORTON GROVE) APPROVAL= - YEAR= 0 DISCONTINUED