e-Drug3D

1091

cas 469-21-6

CLASS

RESPIRATORY
ANTIHISTAMINIC
HYPNOTIC
ANTI-ALLERGIC AGENTS
ANTIEMETICS
ANTITUSSIVE AGENTS
HISTAMINE H1 ANTAGONISTS

ROUTE (list)

ORAL

PK parameters

Cl 11.7 LITER / HOUR (65 KILOGRAM)
t1/2 12.5 HOURHT 12.5 HOUR

MW 270.37
NB_atoms 20
XLogP 2.92
PSA 23.33
NB_HD 0
NB_HA 3
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 019440 (pdf not found) INN (DOXYLAMINE SUCCINATE) UNISOM (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070156 (pdf not found) INN (DOXYLAMINE SUCCINATE) DOXY-SLEEP-AID (PAR PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088603 (pdf not found) INN (DOXYLAMINE SUCCINATE) DOXYLAMINE SUCCINATE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006412 (pdf not found) INN (DOXYLAMINE SUCCINATE) DECAPRYN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1948 NEWMOLECULARENTITY DISCONTINUED
NDA 010598 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) BENDECTIN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1956 DISCONTINUED
NDA 018066 (pdf not found) INN (DOXYLAMINE SUCCINATE) UNISOM (CHATTEM) APPROVAL= AP YEAR= 1978
NDA 088900 (pdf not found) INN (DOXYLAMINE SUCCINATE) DOXYLAMINE SUCCINATE (COPLEY PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 040167 (pdf not found) INN (DOXYLAMINE SUCCINATE) DOXYLAMINE SUCCINATE (PERRIGO) APPROVAL= AP YEAR= 1996
NDA 040564 (pdf not found) INN (DOXYLAMINE SUCCINATE) DOXYLAMINE SUCCINATE (LNK) APPROVAL= AP YEAR= 2004
NDA 021876 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DICLEGIS (DUCHESNAY) APPROVAL= AP YEAR= 2013
NDA 205811 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2016
NDA 209661 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) BONJESTA (DUCHESNAY) APPROVAL= AP YEAR= 2016
NDA 208518 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (PAR PHARM INC) APPROVAL= AP YEAR= 2017
NDA 207825 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212472 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 217000 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (BIONPHARMA) APPROVAL= AP YEAR= 2023